Containment solutions

as individual as your requirements

Containment solutions by Glatt

Containment plays a critical role in the safe handling of a highly potent active pharmaceutical ingredient (HPAPI). It protects operators, preserves product integrity, and ensures compliance with regulatory requirements throughout the entire production process.

Integrated containment solutions for pharmaceutical production

Handling HPAPIs requires more than just standard safety measures. As a global leader in high-containment pharma technologies, Glatt offers integrated containment solutions that cover the entire production cycle – from laboratory and pilot plants to commercial production. Our containment concepts are precisely tailored to your OEB levels, process steps, and plant layouts, enabling safe, reproducible, and compliant pharmaceutical production.

Lab containment technologies

Maximum flexibility, minimal footprint

Our economical containment solution for laboratories offers maximum process flexibility. With the WIBObarrier® system from Weiss Pharmatechnik, it saves a significant amount of space and is extremely cost-effective across the entire process chain – from weighing, granulation, sieving and drying right through to mixing, pelletizing and coating.

For efficient cleaning, the processing unit can be removed from the technical module. This ensures that the technical module is not contaminated and makes the cleaning of the processing unit simple.

As a true all‑rounder, it can be integrated into all process options and pharma containment solutions. In addition, it can be adapted to changing GMP requirements to reliably protect products, personnel and the environment.

Containment technologies for the laboratory

One solution – various opportunities.

Total containment

Safe shielding across the entire production line

Total containment describes a holistic containment concept that goes beyond individual interfaces or components. It ensures that highly potent products remain safely enclosed throughout the entire production process – from material charging and processing to discharge, transport, cleaning and explosion protection.

Glatt’s total containment approach integrates equipment, interfaces and handling systems into a closed, coordinated safety concept, enabling reliable operator protection, product integrity and regulatory compliance across the complete processing line. With patented technologies and decades of containment expertise, Glatt sets the benchmark for total containment solutions in pharmaceutical manufacturing.

Pressure-shock-resistant systems for high-containment pharma

Total containment in high-containment pharma environments requires systems hermetically sealed from the outside world. Glatt’s PRO concept offers complete, absolutely safe production lines for vertical granulators, fluidized bed systems, screens, and product handling components – all in a closed, pressure-shock-resistant design rated at 12 bar. Even in the rare event of a malfunction, no substances escape into the environment.

Clean-in-Place – an essential component of total containment

Clean-in-Place (CIP) is a key requirement for pharma containment solutions. Glatt has developed and patented a full range of CIP-capable components that enable complete cleaning of equipment and production lines without the need to open the system, inspect it manually, or perform additional cleaning. Validation of the cleaning process is integrated into every design. Discover our SC SuperClean® solutions for safe total containment.

TKS containment valve – split butterfly valve for critical transfer points

The TKS containment valve is a key element of Glatt’s containment strategy, developed for contamination-free product transfer at critical interfaces. Based on a patented design with two identical seals, it creates a closed transfer connection between vessels and equipment, enabling safe handling of highly active substances with very low emission levels – even during repeated docking.

The TKS split butterfly valve has proven itself in long-term operation at leading pharmaceutical manufacturers worldwide and combines maximum safety with operational efficiency and a life-cycle-oriented design.

TKS Containment Valve System

Maximum safety & minimal maintenance time.

Learn more about the TKS high-performance split butterfly valve:

Containment solutions integrated from the earliest planning stages

Effective containment starts long before equipment is installed. Containment considerations and a suitable containment strategy play a central role already in the early phases of plant, process and factory planning. From the outset, we work closely with you to develop, evaluate and compare containment concepts and identify the most suitable solution for your specific project requirements.

Our specialists support you in systematically analyzing risks within your process environment, assessing hazard potential and defining containment measures as part of a structured risk assessment. This early integration ensures safe, compliant and cost‑efficient containment concepts throughout the entire lifecycle of your pharmaceutical production.

Let’s plan your containment strategy together!

Contact our experts to discuss your project requirements and develop a tailored containment solution for your production environment.