Continuous Manufacturing / MODCOS

Modular continuous process technology for maximum efficiency, flexibility and product quality

Continuous Manufacturing solution by Glatt, MODCOS

MODCOS – Modular Continuous System

The practice-proven MODCOS (Modular Continuous System) offers the optimal solution for modular and flexible continuous manufacturing processes

With the Modular Continuous System (MODCOS), Glatt offers a highly flexible production platform for continuous manufacturing of coated tablets – from product development to commercial-scale production. The modular, multi‑purpose system can be precisely adapted to individual requirements, enabling short development cycles, fast scale‑up, and maximum process reliability.

The entire process chain of continuous manufacturing is seamlessly covered:

From precise excipient and API dosing to wet granulation, drying, tableting, direct compression and tablet coating. All unit operations are fully integrated into the central GlattView CONTI control system. Consistent product quality is ensured through Process Analytical Technology (PAT) and continuously closed control loops.

Thanks to fully automated, recipe‑controlled processes, every step remains traceable at all times via track & trace functionality. At the same time, the modular system architecture enables rapid product and batch changes – ideal for dynamic production environments.

Your benefits at a glance:

  • Maximum flexibility through variability
  • Consistent and reproducible product quality
  • High efficiency and cost-effectiveness
  • Seamless system integration and customized engineering solutions
  • Transparent process management
  • Wide range of formulations

MODCOS – Direct Compression

Precise dosing, stable process control, reproducible quality through continuous direct pressing

MODCOS offers flexible and customized solutions for continuous direct compression. The various powder components are fed continuously and with high precision via gravimetric multi-ingredient dosing. The system automatically adjusts its hold-up to the respective throughput, ensuring that residence times remain stable and the process is optimally controlled.

Thanks to loss-in-weight dosing technology, the solid material flows are reliably controlled. In combination with Process Analytical Technology (PAT), the amount of material fed remains constant – process stability and reproducibility of product quality are guaranteed at all times.

The integration of downstream process steps such as tableting or capsule filling is carried out directly by Glatt in accordance with customer specifications. This creates a fully connected, continuous production line – from raw material dosing to the finished product.

Performance range: from 5 kg/h to 1,000 kg/h, scalable to individual production requirements.

Why choose MODCOS direct compression?

  • Maximum flexibility
  • Safe operation for operating personnel
  • Quick and easy cleaning

MODCOS – Wet Granulation

Scalable technology for development, piloting, and production

The MODCOS xs-, s-, and m-line systems are specifically designed for continuous wet granulation with subsequent drying. They are ideal for formulation development, feasibility studies, and early-stage process evaluation – from powder to reproducible granules. Manual control enables flexible testing and precise definition of process parameters.

Thanks to robust scale‑up strategies, process parameters defined during development can be seamlessly transferred to larger MODCOS production lines. Modular process units allow targeted adaptation to formulation requirements and production goals – from R&D to commercial continuous manufacturing.

Minimal conversion effort, maximum economic benefit

Within the MODCOS concept, existing GPCG batch granulators can be efficiently integrated into a continuous process chain. This modular integration approach significantly reduces investment costs and enables a gradual transition to state‑of‑the‑art continuous manufacturing technology – without replacing existing equipment.

Your benefits with continuous wet granulation:

  • Modular & scalable process platform
  • Flexible process integration
  • Suitable for demanding products

Get in touch with us!

Discover how our solutions for continuous manufacturing can take your production to the next level – contact our experts today.